Answer:
The answer is reciprocal chromosomal translocation
Explanation:
The Philadelphia chromosome (Ph) is the truncated chromosome 22 generated by the reciprocal translocation t(9;22)(q34;q11) and was first identified in 1960 in a patient with CML [3]. Translocation of the proto-oncogene tyrosine-protein kinase (ABL1) gene located on chromosome 9 to the breakpoint cluster region (BCR) gene located on chromosome 22 results in a BCR-ABL1 fusion gene on the Ph [4, 5]. Three BCR-ABL1 fusion gene hybrids encode BCR-ABL1 protein isoforms p210, p190, and p230, which have persistently enhanced tyrosine kinase (TK) activity. These aberrantly activated kinases disturb downstream signaling pathways, causing enhanced proliferation, differentiation arrest, and resistance to cell death [6, 7]. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 protein are the most successful targeted therapy for Ph-positive leukemia.
True in passive transport molecules move along concentration gradient from high to low concentration
The correct answer is option Observations can be made from outside the "system".
The study of the plate tectonics allows the observation of the movement of the plate tectonics. These observation can be study to determine the pattern of the movement from outside the plate tectonics system and the event occurring due to plate tectonics can be predicted.
Answer:
( Lytic or Lysogenic ) bacteriophage integrate their genetic material into the DNA of the host cell. b)( Lytic or Lysogenic ) bacteriophage infect host cells without killing the host cell. c)( Lytic or Lysogenic ) bacteriophage direct the host cell to produce more viruses that can infect other cells.
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Your sense of taste could indicate that there is something wrong with your car or your health. Tate, gastatory perception, or gustation is one of the five traditional senses that belongs to the gustatory system. Taste is the sensation produced when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue.
