Question in English:
A female carries a recessive lethal gene (l) on one of her X chromosomes, and a normal dominant allele (L) on the other. What is the sex ratio to be expected in this woman's dependency if she marries a normal man?
Answer:
2/3 females
1/3 males
Explanation:
Females have two X chromosomes (XX) and males have an X and a Y chromosome (XY).
The genotype of the female is XLXl. The genotype of the male is XLY, since he is normal.
The possible genotypes are:
<u> XL Xl</u>
<u>XL</u> <em>XLXL XLXl</em>
<u>Y</u> <em>XLY </em><em>XlY</em>
<em />
All female offspring will be normal as they will always have one normal copy of the X chromosome from their father.
50% of the male offspring will be normal, but 50% will inherit the lethal gene from their mother.
Because the allele is lethal, that means XlY males will not be born.
That means 2/3 of the children will be females, and 1/3 will be males.
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