The American Revolutionary war is considered to be the widespread and most damaging to America Indians.
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Explanations:
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American Revolutionary war is considered to be the main reason which made a major setback for the American Indians. To put an end to territory expansion of the American people in establishing colonies in the Indians territory they formed an alliance with British people and to fight against Americans.
Actually, the American Revolutionary war was happened in the east and west. In the east, it was a war against the British dominance and in the west, it was a war between the Americans and the Indians it was also called as Indian war.