Answer:
1. Binding of insulin to the alpha subunit of the insulin receptor
2. Activation of insulin receptor tyrosine kinase
3. Phosphorylation of IRS proteins
4. Activation of PIP3-dependent protein kinase B (PDK1)
5. Phosphorylation of phosphinositide 3-kinase (PI-3K)
6. Conversion of PIP2 to PIP3
7. Activation of Akt
8. Glut4 receptors transported to cell membrane
Hello there ^ _ ^
I believe the answer is : A - Evolution
Good luck!
C.
Biotic mean alive, so we can cut off the first 2 easily. Aquatic birds eat frogs, so that one is safe for now. A decrease in something parasitic usually helps the population, so D is out too. The only one left is C.