2.5 billion years ago
you're welcome :)
-56.6 Celsius is approximately the freezing point of carbon dioxide.
In spherocytosis, there is a defect in the membrane proteins of the red blood cells, specifically ankyrin and spectrin. These membrane proteins contribute to the biconcave shape of red blood cells therefore the loss of these proteins will lead the red blood cells to lose its biconcave shape--leading to abnormally shaped red blood cells (spheres) hence the name. This can lead to premature destruction of red blood cells and jaundice due to hyperbilirubinemia. Spherocytes do not hold oxygen and carbon dioxide well as spherocytes have a decreased surface area.
1/4 if by express you mean in the genotype
1/2 if by express you mean in the phenotype
These would be any cells that reproduce asexually, like bacteria