If a mouse inherits a deletion in the shh enhancer, what effect would you expect to see?

2 answers:

4 0

You would expect to see abnormal limb development.
A long-range shh enhancer regulates expression in the developing limb and fin is associated with preaxial polydactyly. Consequences of deletion and mutation of the limb enhancer in a mouse would be an abnormal development of the limb which is regulated by the Shh enhancer.

Liula [17]3 years ago

3 0

Abnormal limb development

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