Answer:
C. The enzyme with mutation 1 has decreased affinity for pyridoxal phosphate, whereas the enzyme with mutation 2 has lost the ability to bind to the substrates.
Explanation:
A coenzyme is an organic cofactor that binds with an enzyme in order to initiate or aid the function of the enzyme. A coenzyme binds to the active site of the enzyme (where the reaction occurs), thereby triggering its activation by modifying protein structure during the reaction. Some examples of coenzymes include Coenzyme A and Adenosine triphosphate (ATP). Pyridoxal phosphate is a coenzyme (it is the active form of vitamin B6) that is required for the function of cystathionase. Moreover, cystathionase is an enzyme that enables cells the synthesis of cysteine from methionine (transsulfuration pathway). The binding of pyridoxal phosphate to the enzyme increases the binding affinity of the enzyme for the substrate, thereby influencing its activity. In this case, it is expected that mutation 1 reduces the binding affinity of the enzyme to the cofactor, and thereby the cofactor is required at a higher concentration to restore normal enzyme activity.
Mitochondria since it’s the power house of the cell where the energy for this one is produced
Answer: Heart Rate
Explanation:
When you are running in a race, one feedback mechanism that happens as you increase exercise and muscle activity is that, your heart rate also increases. Your heart rate increases because it needs to sustain the body's need of more energy to be supplied to the different parts of the body during an activity.
Answer:
Coronary Artery
Explanation:
A blockage by blood clot formation is coronary artery called as thrombus reduces the blood flow to the heart. The reduced blood flow causes the heart to dysfunction and the myocardial infarction occurs. Heart tissue can sustain serious damage upon such a shock.
