In phase II of the SBIR grant process are funds used to create a prototype of a product or service.
SBIR segment II projects commonly run for twenty-four months, even though deviations are feasible relying on the instances of the proposer and the studies venture. Whilst a financial institution offers a line of credit, a is classed at the start of the mortgage. lengthy-time period loans from business banks are normally easily available to small startup firms. The five of credit are individual, capability, collateral, capital and competence
Phase III refers to work that derives from, extends, or completes an effort made below earlier SBIR funding agreements, however is funded by means of assets other than the SBIR application.
An SBIR investment agreement is a agreement entered into between an SBIR collaborating federal enterprise and a small enterprise problem for the overall performance of experimental, developmental, or research work, together with services or products funded in complete or in element by the federal government.
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Answer:
to compare values across a few categories
Explanation:
Answer:
A. Natural killer (NK) cells are activated in response to interferons or macrophage and Major histocompatibility complex (MHC) and allows direct apoptosis of virus.
Viruses can invade NK cells by inhibiting MHC from reaching the cell surface. Using stimulating the inhibitory receptors and disrupting the activating receptors, viruses can avoid NK cells. MHC act as a ligand of inhibitory receptor, and when bind with inhibitory receptor allows damage to NK cells.
So, if i would be a virus i will use inhibitory receptors stimulation to avoid NK cells.
B. Bacteria are killed by phagocytic immune cell macrophages by engulfing them.
Bacteria avoid macrophages by escaping from phagosome before the lysosome fuses as lysosomal chemical kill the bacteria and some bacteria prevent acidification of the phagosome.
C. Parasites can avoid macrophages by modulating the host's cell cytoskeleton to block proper phagocytosis.
D. Bacteria can avoid dendritic cells by avoiding lysosomal degradation and prevent antigen presentation on MHC molecules that will modulate the entrance to DCs.
E. B cells are responsible for producing antibodies. Activation of B-cell depends on positive and negative signals transmitted through the B-cell receptor (BCR), so genetic polymorphisms and mutations affects the positive and negative signals. If mutation is done showing negative signal, B cell will not the activate and no antibodies will produce.
