The cellular and genomic organisation of prokaryotes are different from that of eukaryotes. Prokaryotic cells have a small, simple structure compared to eukaryotic cells. -less surface area per volume. -simpler and smaller genomes than eukaryotes. - the genome consists of a ring of DNA with few associated proteins. -prokaryotes do not have membrane-bound organelle for respiration but many enzymes needed for cellular respiration are attached to the plasma membrane, which may fold and extend into the cell. -Ribosomes are the only cytoplasmic organelles in prokaryotes and they are not membrane-bound.