Answer:
Those capillaries that have endothelial cells tightly attached have an increase in cell-to-cell junctions, such as desmosomal junctions that are poorly permeable to substances.
These capillaries generally function as conductors or collectors and not as permeabilizers like the pulmonary capillaries that are fenestrated and allow a high passage of substances and gases.
The capillaries are waterproof and prevent the passage of substances or fluids such as in the blood-brain barrier that is very selective
Explanation:
The blood-brain barrier is too selective since it is not favorable for the organism that many fluids, drugs, substances or chemical compounds enter the brain space.
This is the reason why the vessels are waterproof and why pharmacology was challenged to invent drugs that could cross this barrier since it was considered impossible.
An example is dopamine, which in parkynson's disease the levo group is added to dopamine, thus forming levodopamine as a product, this is the only way that the drug crosses the blood-brain barrier and can pass the impermeable barrier generated by capillaries with endothelial cells that are close to each other or closely linked
<span>The change in the position of any object in a given time is known as motion.</span>
Answer:
I think the answer for your question is the letter c
The series of events that take place in a cell<span> leading to its division and duplication (replication) that produces two daughter cells. </span>
Answer:
For both actin and microtubule polymerization, nucleotide hydrolysis is important for decreasing the binding strength between subunits on filaments.
Explanation:
Cytoskeletal filaments are common to eucaryotic cells and are impotartant to the spatial organization of cells. Intermediate filaments provide mechanical strength and resistance to shear stress. Microtubules determine the positions of membrane-enclosed organelles and direct intracellular transport. Actin filaments determine the shape of the cell's surface and are necessary for whole-cell locomotion. A large number of accessory proteins are present that link the filaments to other cell components, as well as to each other. Accessory proteins are essential for the assembly of the cytoskeletal filaments in particular locations, and it includes the motor proteins that either move organelles along the filaments or move the filaments themselves.
Actin filaments and microtubules are assembled with expenditure of energy i.e the ATP/GTP tightly bound to actin/tubulin is irreversibly hydrolyzed to ADP/GTP during the assembly process, and liberation of Pi in the medium occurs subsequent to the incorporation of subunits in the polymer. Pi release acts as a switch, causing the destabilization of protein-protein interactions in the polymer, therefore regulating the dynamics of these fibres. The progress is made in four areas: the chemistry of the NTPase reaction; the structure of the intermediates in nucleotide hydrolysis and the nature of the conformational switch; the regulation of parameters involved in dynamic instability of microtubules; and the possible involvement of nucleotide hydrolysis in the macroscopic organization of these polymers in highly concentrated solutions, compared with the simple case of a equilibrium polymers.
