Disruption of axonal transport would be a good target for his drug.
<h3>What is disruption of axonal transport?</h3>
- Axonal transport defects are among the early molecular events leading to neurodegeneration in mouse models of amyotrophic lateral sclerosis (ALS).
- Gene expression profiles indicate that dynactin-1 mRNA is downregulated in degenerating spinal motor neurons of autopsied patients with sporadic ALS.
- Disruption of axonal transport also underlies the pathogenesis of spinal muscular atrophy and hereditary spastic paraplegias.
- The neurotoxin β,β′-iminodipropionitrile (IDPN) selectively disrupts slow axonal transport without affecting fast anterograde or retrograde axonal transport.
- Impairment of slow axonal transport causes a proximal accumulation of neurofilaments.
- Because neurofilaments regulate axonal diameter, this accumulation leads to a marked swelling of the axon.
- Acrylamide causes decreased axonal transport, also causing proximal accumulations of neurofilaments and swelling.
To learn more about axonal transport,
brainly.com/question/10600853
#SPJ4
an element on the periodic table
Answer:
Tropomyosin
Explanation:
The calcium binding to troponin and induces the muscle contraction. The active binding site gets exposed due to the calcium binding.
The calcium ions then attaches with troponin molecule. This changes the shape of troponin and removes the tropomyosin protein from the binding site. No ATP is available during this process.
Thus, the correct answer is option (d).
Herbivores. The eat directly from the producers. 10% of the producer's energy goes to herbivores, while only 10% of the 10% energy the herbivores had goes to carnivores.
You can't use it because the living cells won't be able to handle the high vacuum conditions.
Hope this helped ;)
