Bacteria were first observed by the Dutch microscopist Antonie van Leeuwenhoek in 1676
<u>-TheUnknownScientist</u>
You may be referring to the cytoplasm here. That is the "filling" within the cell. But if you are looking for specific transport of proteins, the ER folds proteins and then transport vesicles move them to the Golgi.
B. 2.883 million kilometer