Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
Answer:
Mid-ocean ridges
I think
Sedimentary rock is one of the three main rock groups (along with igneous and metamorphic rocks) and is formed in four main ways: by the deposition of the weathered remains of other rocks (known as 'clastic' sedimentary rocks); by the accumulation and the consolidation of sediments
Answer:
Sinkholes can occur when<u> excessive water use lowers a water table and weakens the substrate.</u>
Explanation:
There are various causes for sinkholes, but all are related to water and how this can affect the soil. One of the causes of sinkholes is the excessive use of water. Excessive use lowers the volume of water in aquifers. As a consequence, the substrates that are above the aquifer change. They can not support large amounts of weight, leading to a sinkhole and soil with low permeability.
C. can't make their own food.
Fungi are considered to be more closely related to animals rather than plants because they
NOT:
A. are photosynthetic. B. aren't mobile. <span>D. are multicellular.</span>