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4 years ago

Job on enzyme, substrate and active site

1 answer:

8 0

These pockets contain the active site, which is the area of an enzyme where the substrate binds and the chemical reaction takes place. In the active site, amino acids of the enzyme protein will bind to the substrate. ... When binding to a substrate, enzymes may undergo an induced fit.

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Which is the best description of the two organisms highlighted in orange?

never [62]

Answer:pls add a picture so we can see the organisms

Explanation:

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2 years ago

From a chemical view, how is an amino acid is being recognized by its specific aminoacyl tRNA synthetase?

hammer [34]

During translation, rRNA and tRNA read mRNA in 5´ to 3´ direction. According to the codons being readen, tRNA transfers the correct amino acids to build the polypeptide chain. A codon is a short sequence of three nucleotides that store the genetic information for the aminoacids´ assembly.

Each tRNA has two important sites. One of them that couples with the codon of the mRNA molecule, named anticodon. The other site couples with an amino acid through the action of the aminoacyl-tRNA synthase enzyme. The whole complex, amino acid + enzyme + tRNA is named aminoacyl-tRNA.

Each tRNA is recognized by a specific aminoacyl-tRNA synthase enzyme. The enzyme is also capable of recognizing a specific amino acid. Let us say, for instance, that tRNA is specific for phenylalanine. The molecule is attached to the enzyme that is specific for that tRNA(Phe). Then, when the enzyme and tRNA(Phe) are together, they get to find phenylalanine. The enzyme links the aminoacid to the RNA. Once the whole complex is formed, the tRNA gets to pair its anticodon with the mRNA codon. This is,

Recognition of enzyme and the specific tRNA(aa) ⇒ aa being aminoacid
Recognition of enzyme and the specific aminoacid
Linkage of the aminoacid to RNA by the enzyme action
Pairing of tRNA anticodon to mRNA codon.

Considering that there are twenty amino acids available, there are also twenty complexes of aminoacyl-tRNA, one for each amino acid. Each of the mRNA codons represents one of the 20 amino acids used to build the protein. Each amino acid can be codified by more than one codon. Of the total 64 codons, 61 codify amino acids, and one is a start codon. The left three codons are stopping translation points.

tRNA decodes genetic information from the nucleotidic sequence in the mRNA molecule and allows amino acids to align composing the new protein.

Once the new peptidic link joins, placing together the new amino acid to the growing peptidic chain, the binding between the amino acid and the tRNA molecule breaks. The tRNA is now free to join another amino acid and repeat the cycle.

In conclusion, a specific aminoacyl-tRNA synthase enzyme recognizes a tRNA, which is also specific for a certain amino acid. When together, the enzyme recognizes the amino acid and links it to the RNA. The whole complex is known as aminoacyl-tRNA. Once the tRNA is joined to its amino acid, it gets to pair a codon of mRNA to add that amino acid to the new synthesizing protein.

6 0

3 years ago

Estimated percentage of afflicted individuals

devlian [24]

Answer: About 1 in 200,000 people in the United States are born with syndrome A ... Prevalence, The prevalence of a gene mutation or a genetic disorder is the ... Can a change in the number of genes affect health and development

Explanation:

6 0

3 years ago

Describe how different types of models could be used to research a disease. Make a list of questions you would ask.

Leto [7]

Answer:

A disease model is an animal or cells displaying of the pathological process that are observed in the actual human or animal disease.

8 0

3 years ago

Read 2 more answers

Those with generalized anxiety disorder are likely to have overactivation of _________________ with anxiety-provoking events:

Novay_Z [31]

Answer:

Explanation:

When an individual experiences excessive and continuous worry and anxiety about certain events of life(families,job security} to the extent that this happens uncontrollably in the subject, and difficult to control, such neurological disorder is called generalized anxiety disorder (GAD).

It is caused by over activation or stimulation of the region of the brain(amygdala) that mediate response to fight and flight stimulus and fear.

It is usually diagnosed when the inability to control worries extends beyond days to months with symptoms like poor concentrations, overthinking ,indecision, inability to relax, continuous taking every event as life threatening and disrupted sleep patterns.

Generally, sensory stimuli of fear or danger in the brain are transmitted by two brain circuits to two regions of the brain, to the peripheral cerebral cortex for processing voluntary decisions about the situation, and the Amygdala for processing involuntary emotional decision.

Physiologically; it is the amygdala that processes how the body reacts to the effects of the stimuli in the immediate environments, the influence of the stimuli on the emotions of the subject, and the involuntary response to the stimuli by the subject.

In response to the sensory stimuli of fear It stimulates the hypothalamus, which in turn activate the circulatory and breathing centre of the brain.Therefore,hormones(adrenaline) are released into the blood stream to increase blood pressure, heartbeat, breathing rate, muscle contractions and other involuntary response to anxiety. This gives a fast response compare to the cerebral cortex which takes time to relay response.

Amygdala, generally stores memories of all emotions, fear, and anxiety. In GAD patients, their Amygdala is sensitive and had been adapted to the storage of fear and anxiety to the extent that every slight normal event which does would not portend danger is over reacted to with fear or flight response which triggers the two brain circuits described above to give anxiety-provoking events.

Intake of drugs, psychotherapy are the mode of treatments.

4 0

3 years ago