Hydrolysis is when a polymer (such as a peptide bond or fatty acid) is split into smaller segments by adding water.
Such changes would occur mostly likely near or in the active binding site of the enzyme.
Because the drugs used are competitive inhibitors of the <span>HIV reverse transcriptase enzyme, it means that they connect directly to the active binding site of this enzyme not allowing it to preform its function. If the mutations impede this drugs to work, it is probably because they alter the active binding site of the enzyme, not allowing the drug to bind and have its competitive behaviour permitting the enzyme to work normally. </span><span /><span>
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The coenzyme required is pyridoxal phosphate. It is a vitamins B6 cofactor required for transamination reaction.
Answer:
I would start on Evaporation. I will then have to go through condensation, then precipitation, then a surface runoff then into groundwater which will start the evaporation process all over again :)