Cholera toxin locks the G-subunit into an active state, in that GTP is bound and cannot be hydrolyzed back to GDP to turn off the subunit. This leads to a subsequent activation and increase in adenylate cyclase inside the cell. This increases the level of cAMP which leads to cytolysis of the cell.
The cholera toxin is released from a bacteria known as <em>vibrio cholera</em><em>. </em>This bacteria is gram-negative and releases this toxin into the body which leads to manifestations like vomiting, increased heartbeat, watery diarrhea, cramps in the muscles and a low blood pressure. When this toxin is released into the body. The toxin activates adenylate cyclase and increases its level. This in turn increases the level of cAMP. This initiates a signaling cascade which effects the osmotic pressure of the cell. This leads to subsequent cytolysis of the cell.
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Answer:
No es la principal función.Es falso
Answer:
C. Global Climate Change
Explanation:
When fossil fuels are burned, they release carbon dioxide and other greenhouse gases, which in turn trap heat in our atmosphere, making them the primary contributors to global warming and climate change.
For the transport of metals across the fluids and the body membranes, the intracellular potential is needed. But sometimes due to the toxicity of lead, the process is affected especially in the digestive tract.
How bioaccessibility of lead is affected in the human digestive tract?
Both the organic (tetra alkyl lead) and inorganic forms of lead have been demonstrated to be extremely hazardous in experimental studies. This lead absorption, which typically occurs by inhalation or food contamination, is influenced by variables including absorption rate, particle size, and solubility. The majority of the lead that is inhaled is in tissues that contain minerals. Following speciation, Lead's binding power increases in comparison to Zinc and Calcium, which has an impact on fluidity. Lead's bioavailability seems to be reduced when food is present. The concentration of lead may also be reduced by pyromorphite. Since solid state speciation happens when the pH is between 6 and 7, Now, this results in a change in circumstances from the stomach to the intestinal tract, leading lead to transform into lead phosphate, which is less soluble and reduces bioaccessibility.
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