In yeast cells, an endonuclease Spo11 introduces double-strand DNA breaks for chromosome pairing. Identify a rightstatement expl
aining about the Spo11.a) Spo11 cleaves DNA only at specific DNA sequenceb) Spo11 cleaves DNA without DNA sequence specificityc) Spo11 only cuts DNA chromosomal regions that are tightly packed with nucleosomesd) Spo11 only cuts DNA chromosomal regions containing telomere DNA
The best response to the question: Identify a right statement explaining about Spo11, would be, A: Spo11 cleaves DNA only at specific DNA sequences.
Explanation:
Spo11 is a protein present in eukaryotic cells that is part of the process of cleaving, formation, recombination and repair of DNA double strands when the process of meiosis takes place. This ensures that the correct pairing of genes is present and that the resulting DNA strands will be functional. Although a lot is still not known about the exact process, it seems that Spo11 is one of the proteins responsible for producing the cleaving of DNA strands through a pretty complex chemical process. However, what it is known is that this protein can usually be found on the 5´ terminals of the DNA strands, and they cleave portions of it so that these portions can later be recombined with their pairs appropriately enough to make the new formed strands fully functional and their home cells also functional.
