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belka [17]
3 years ago
9

Name the process in animals which requires meiosis to take place

Biology
1 answer:
grin007 [14]3 years ago
3 0
Sexual reproduction is the process in animals that requires meiosis to take place. It does not matter whether the animal is single celled or multi celled. Meiosis is the type of cell division in which four daughter cells are formed with half the number of chromosomes of the original orthe parent cell. The perfect example of meiosis is the formation of gamets and spores. Meiosis is the process that helps in the formation of male and female reproductive cells like the sperm and the eggs. Meiosis is totally different from mitosis.
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Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.

Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.

However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.

meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.

We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.

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Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.

Learn more about breast cancer here : brainly.com/question/6747562

#SPJ4

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