All categories

3 years ago

Mutations in ubiquitin lead to malfunction of what organelle in ALS that leads to buildup of mis-folded proteins?

Biology

1 answer:

sergiy2304 [10]3 years ago

8 0

Answer:

Mitochondria.

Explanation:

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which the neuron died due to mutation in superoxide dismutase 1 gene. This disease is also known as Lou Gehrig's disease.

Mitochondria structure is disorganized in ALS. The ubiquitin protein mutation leads to the malfunctioning of mitochondria and misfolded proteins are made in the mitochondria.

Thus, the correct answer is option (a).

You might be interested in

What are structures that form when magma solidifies beneath Earth surface called ?

zhannawk [14.2K]

Answer:

Intrusive Rock

Explanation:

Intrusive Rock - Igneous rock that forms when magma hardens beneath Earth's surface.

<em>Hope this helps</em>

<em>-Amelia The Unknown</em>

5 0

3 years ago

What structure is the outermost, dense covering around bone?

lesya692 [45]

Answer:

SADSFADVADVADADVADVADVADVADVADVADVADADADSVADVADADSVADVADAVVVVVVVVVVVVVVVVVVVVVVVVVVVV

Explanation:

6 0

2 years ago

In will love biology please help me

Savatey [412]

Answer:

Ive never seen someone with white eyes, so im guessing its that one...

Explanation:

7 0

2 years ago

When the sun depletes its current core fuel, it will become a _____.

erica [24]

I think the answer would be "A"

4 0

2 years ago

Read 2 more answers

atch the statement to the following options.A. One of a pair of chromosomes with similar genetic information and from different

Goryan [66]

Answer:

A. Homologue.

B. Chiasma.

C. Synaptonemal.

D. Synaptonemal.

E. Synapsis.

Explanation:

Genetics can be defined as the scientific study of hereditary in living organisms such as humans, animals and plants.

Synaptonemal complex can be defined as a network of proteins that is responsible for holding homologous chromosomes (homologues) together.

Generally, a synaptonemal complex (protein lattice) is formed between homologous chromosomes during mitosis and meiosis. Also, synaptonemal complex is important for the formation of the four sister chromatids referred to as tetrads.

Furthermore, the synaptonemal complex (protein lattice) has a tripartite structure which comprises of the following components;

I. SC protein-1 (SYCP1).

II. SC protein-2 (SYCP2).

III. SC protein-3 (SYCP3).

In conclusion, the synaptonemal complex plays a significant role in synapsis, recombination and chromosome pairing.

Matching the various terminologies in genetics with their description, we have;

A. Homologue: one of a pair of chromosomes with similar genetic information and from different sources like the sperm and egg.

B. Chiasma: several X-shaped structures may be visible under the microscope and indicate where crossing over has occurred.

C. Synaptonemal: a lattice of protein holds two replicated chromosomes in precise register with one another.

D. Synaptonemal: four chromatids are held together by a zipper-like structure.

E. Synapsis: a process in which pairs of homologous complex chromosomes line up side by side.

5 0

2 years ago