Answer:
The correct sequence is 1, 2, 3, 4, 5 and 6.
Explanation:
An extreme allergic reaction to food, venom, or medicine is termed as anaphylaxis. However, the majority of the cases of anaphylaxis occur due to the consumption of foods like tree nuts or peanuts or by stinging of a bee. Some of the signs of the condition are low pulse, rashes, and at certain occasions shock, also called anaphylactic shock.
The following is the chronological order of the events that take place during the generation of an anaphylactic reaction are:
1. The binding of the IgE molecules takes place with the basophils and mast cells.
2. The cross-linking takes place between the antigen and the neighboring IgE molecules.
3. The process of degranulation takes place.
4. Discharging of chemical mediators like histamine takes place.
5. An elevation in smooth muscle contractions and capillarity permeability is witnessed.
6. Finally, the eosinophils and neutrophils move towards the affected region.
