Question

"The total concentration of receptors in a sample is 10 mM, and the concentration of free ligand is 2.5 mM. Calculate the percentage of receptors that are bound to ligand. Enter your answer as a number only (no percent symbol)."

Answer 1

Answer:

16.66 %

Explanation:

The receptors that are bound with the ligand can be calculated by the formula as follows:

Kd = [R] [L]/[RL]

Here, Kd is dissociation constant = 1.5 mM

R is free receptor concentration = 10 mM

L is free ligand concentration = 2.5 mM

The values needs to be constitute to find the percentage  of receptors that are bound to ligand.

Put all the values

1.5 = 10 × 2.5 / RL or RL = 25 /1.5

So RL = 16.66

Hence 16.66 % of receptor is bound to substrate.

Thus, the answer is 16.66%