Answer:
In my opinion, they didn't.
Explanation:
The "Indian Removal" refers to a time period when a lot of native American people were forced to get out from their ancestral homes. The reason for this was because the US government wanted to obtain control over the natural resources that exist within these lands. In return, they gave the Native American people with a set of land that they called "Reservation".
But, the value of the reservation land was nothing compared to the value of the land that was taken away from them. (Both from cultural and economic point of view). This action prevented the Native American community to develop their community and massively reduced their social influence in United States.
If affected Indian life because it decided where they were allowed to go, what they could eat and wear, and what their jobs are.
If the point was between north and east it would be northeast.