“They can be thought of as "factories" in the cell”.
Answer:
Gene therapy is a medical field which focuses on the utilization of the therapeutic delivery of nucleic acids into a patient's cells as a drug to treat disease.
Geological change will not cause a mass extinction, because it happens on a too big scale - on the scale of millions of years. During such long time, it is more likely that other causes will influence the survival of extinction of species, such as climate change or environmental disasters, and even if there is a small influence, it would not be significant next to other causes.