Garrod hypothesized that "inborn errors of metabolism" such as alkaptonuria occur because...genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes.
Explanation:
Archibald Garrod researched on alkaptonuria and proposed the ‘one gene-one enzyme’ hypothesis. This led to the finding that alkaptonuria is caused due to an inherited or “inborn error of metabolism”.
This hypothesis stated that each gene codes and responsible for a single specific enzyme which facilitates a particular step in the metabolic processes.
According to Garrod, a mutation of a particular gene leads to specific error or defect leading to a lack of a particular enzyme that takes part in the biochemical metabolic pathways. This disrupts the metabolic pathway at the specific enzymatic action point.
In alkaptonuria, it was found that the defective phenotype of dark urine is due to the inborn error happening during the waste elimination process.
Answer:
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Explanation:
puberty is the period during which adolescents reach sexual maturity and become capable of reproduction.
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Answer:</h2>
After instruction about care while at home this statement <u>"I should contact the doctor if my temperature is 100.4° F (38°C) or higher.</u>
" indicates effective teaching.
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Explanation :</h2>
Because there is an increased risk of infection in the client , so , when the client says that she will contact the doctor if her temperature is 38° C (100.4° F) or greater , successful teaching is indicated.
The client should be instructed that he should monitor her temperature two times / day.
The client should avoid all the activities which can cause infection i-e from coitus, douching, and tub bathing.
As water in shower doesn't enter the vagina and increase the risk of infection ,showering is permitted .
A fluid intake of at least 2 L daily is recommended to prevent potential urinary tract infection.
We get tired after exercise because our muscle fibers get tired very quickly. This is due to the major source of energy for the muscle tissue, called adenosine triphosphate, or ATP. As the muscles make use of this supply of energy, they get tired and fatigue.