After metaphase is complete, the cell enters anaphase. During anaphase, the microtubules attached to the kinetochores contract, which pulls the sister chromatids apart and toward opposite poles of the cell (Figure 3c). At this point, each chromatid is considered a separate chromosome.
<span>The Ostrogoths' kingdom was separated from central europe by the ALPS, while the Anglo-Saxons' kingdom was separated from the rest of Europe by the -ENGLISH CHANNEL -- as we would call it today. Then they might have called it by the ancient name (from Ptoltemy) - "Oceanus Brittanicus" or the Anglo-Saxons would have called it the "South Sea."
</span>
The first known pandemic was the Plague of Justinian, which took place in the Byzantine Empire in A.D. 542, it struck its capital Constantinople, part of the Sassanian Empire in the Middle East and several cities across the Eastern Mediterranean Sea. Modern scholars think it started in Central Asia.