The mechanism of action of Bordetella pertussis is to stop the cilia of epithelial cells from beating.
<em>Bordetella pertussis</em> is a pathogenic, gram-negative bacteria. It is the causative agent of highly communicable respiratory disease known as pertussis or whooping cough.
The mechanism of action of Bordetella pertussis:
- This bacterium colonizes the ciliated epithelial cells of the respiratory airways of the host.
- A surface protein on the bacteria called filamentous haemagglutinin adhesin binds to sulfatides on the cilia of epithelial cells. When the bacterium is anchored, it releases tracheal cytotoxin, which prevents the cilia from beating.
- As a result, the cilia in an organism's lungs are unable to sweep out foreign material, and the body reacts by causing the host to cough. When people cough, bacteria are released into the air, where they might spread to other hosts.
- Another toxin called the pertussis toxin, often known as PTx, prevents adenylate cyclase from using ATP to convert to cyclic AMP. This results in over-conversion of ATP to cyclic AMP, which may interfere with cellular signaling systems. As a result, phagocytes are unable to respond to an infection effectively.
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You can experience a transfusion reaction
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Answer:
100%
Explanation:
A pea plant homozygous for the trait of smooth seeds;
let that be = ss
A pea plant that is homozygous for the trait of wrinkled seeds;
let that be = ww
if ss crosses with ww; the F1 produces seeds that are all smooth
i.e ss × ww = (sw, sw, sw, sw)
From the question, we are to find the percentage of the second generation that will produce smooth seeds after self fertilization occurs.
i.e sw, sw, sw, sw × sw, sw, sw, sw
= the result will yield ssww for all F2 progeny
∴ the percentage of plants that will have smooth seeds when the F1 generation is self-fertiized is 100%
The scientist that presented that deoxyribonucleic acid contained equal quantities of certain nitrogen bases is Chargaff. In addition, Chargaff’s rules state that deoxyribonucleic acid from any cell of all organisms must have a 1:1 ratio which is base pair rule of pyrimidine and purine bases and more precisely that the total of guanine is equal to cytosine and the total of adenine is equal to thymine. This configuration is found in together strands of the deoxyribonucleic acid.
Answer:
Explanation:
Cancer is unchecked cell growth. Mutations in genes can cause cancer by accelerating cell division rates or inhibiting normal controls on the system, such as cell cycle arrest or programmed cell death. As a mass of cancerous cells grows, it can develop into a tumor.