1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
IceJOKER [234]
3 years ago
6

Describe the process of altering the genetic variation of a cell using a genetically modified virus for human gene therapy. In t

he future, how may this effect the gene pool?
Biology
1 answer:
Len [333]3 years ago
3 0
In human gene therapy, a genetically modified virus (a.k.a. a viral vector) can alter the genetic variation of a cell, but not all viral vectors do.

The process often begins with the delivery of or creation of a segment of viral double stranded DNA (containing the gene you want to introduce). Then typically an enzyme known as an integrase cuts the ends of the segment of viral DNA and also cuts open the cell's DNA. Then the viral DNA is integrated/ inserted into the cell's DNA. The connecting ends are ligated together and adjusted so that the nucleotide base pairs match up.

This in the future may affect the gene pool for instance if the viral DNA (your gene) was inserted in the middle of another gene or important regulatory sequence of the cell DNA, and this alteration may be passed on into offspring and become present in the gene pool, which could have bad effects.

The effects on the gene pool really depends on what the virus ends up doing. For example, it may fix the function of a damaged gene which is the goal, and allow for a working gene to be in the gene pool, which would be good. The problem with gene therapy is that it's difficult to predict 100% what the virus will do every time it is given to a patient.

But it's very important to consider that it will only affect the gene pool if the virus is able to enter and alter germ cells (reproductive cells). If the virus, enters somatic cells (regular body cells) this will not be passed on to future generations. So viruses can be designed to avoid germ cells and avoid this gene pool issue. Also, some viral vectors use viruses that do not integrate their DNA, the cells just express the viral DNA (create the desired protein from it) and over time the viral DNA is degraded/ lost which wouldn't pose this threat.

This is long, but I hope it helped!
You might be interested in
Which part of the brain is responsible for coordinating muscle movements and maintaining balance?
mr Goodwill [35]
The Cerebellum is responsible for coordinating muscle movements and maintaining balance
7 0
3 years ago
Organiza los siguientes conceptos en orden cronológico: 1) Fotosíntesis 2) Respiración aeróbica 3) Primeros organismos eucariont
Crank
<h2>respiracion aerobic</h2><h2>fotosintesis</h2>

organismo Eucaronte

<h2>pluricelular</h2><h2>reproduciion  </h2><h2 /><h2 />

8 0
3 years ago
De qué manera un cambio en la secuencia del gen que codifica para una de las cadenas de la hemoglobina puede afectar la función
krek1111 [17]

Answer:

Please put this question in English and I would then love to help you. Thanks.

3 0
3 years ago
What would happen to a coral reef if sea levels suddenly rose?
alex41 [277]

when the see levels rises the great barrier reef will have less and less fishes

4 0
3 years ago
Please explain to me the basic difference between Darwinism and Neo -Darwinism. It gets me totally confused. Thank you!
aleksandr82 [10.1K]

Answer:

Darwin was able to explain evolution with evidence, something Lamarck did not do.

Explanation:

Lamarck and Darwin both were scientists who tried to understand the concepts of evolution. Lamarck's theory of evolution was based upon how living organisms vary during their lifetime, and after that they pass these changes to their offspring. While on the other hand Darwin's theory was very much based upon evidences and practical explanation that is why his theory became accepted and Lamarck's wasn't.

7 0
3 years ago
Other questions:
  • What helps determine how easily magma flows?
    10·2 answers
  • The recommended daily allowance (RDA) of the trace metal magnesium is 410 mg/day for males. Express this quantity in μg/day.
    6·1 answer
  • When a neutrophil discharges its enzymes into the tissue fluid?
    13·1 answer
  • What occurs during absorption
    5·2 answers
  • All of the following are examples of organic matter soil except
    9·1 answer
  • URGENT!!!! Active and passive transport.<br> Use the image
    10·1 answer
  • Help please someone please
    8·1 answer
  • is it possible to get pregnant a woman if she have a very small egg cell? in comparison a normal egg cell would be like a size o
    10·2 answers
  • Compare and contrast the rock cycle and the carbon cycle
    15·1 answer
  • Much of the coordination of vertebrate body functions via chemical signals is accomplished by the ________.
    9·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!