Answer:
The correct answer will be option-E
Explanation:
Hershey and Chase's experiment was performed to test whether DNA serves as the genetic material or protein.
To perform experiment they grew bacteriophage into radiolabeled phosphorus and sulfur compounds. The phosphorus is an integral part of the structure of DNA whereas proteins contain sulfur in their structure.
In the given condition if radiolabeled nitrogen is utilized then the experiment will fail as the structure of proteins also contains an amino group( NH₂) in their structure as well as DNA. The scientist will not be able to identify whether the DNA is the genetic material or protein.
Thus, option-E is the correct answer.
The answer is ‘suspect iii has 900 bp and 260 bp sized DNA fragments’
Forensic science utilizes particular sequences of DNA that are unique to people and are cut differently by restriction enzymes. These techniques are referred to as Restriction Fragment Length Polymorphism (RFLP) and the Short Tandem Repeat (STR) Analysis. In this case, there is an exact match on the crime sample and that of the suspect.
Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Answer:
the possible gametes are Aa,Aa,Aa,Aa
