Answer: The number of available symptomatic treatments has markedly enhanced the care of patients with Amyotrophic Lateral Sclerosis (ALS). Once thought to be “untreatable”, patients with ALS today clearly benefit from multidisciplinary care. The impact of such care on the disease course, including rate of progression and mortality, has surpassed the treatment effects commonly sought in clinical drug trials. Unfortunately, there are few randomized controlled trials of medications or interventions addressing symptom management which has resulted in the need for physicians to base their selection of specific therapies upon personal experience and anecdotal reports (1 Forshew). In this review, we will provide the level of evidence, when available, for each intervention that is currently considered “standard of care” by consensus opinion.
Explanation:
A critical evaluation and synthesis of research studies focusing on a specific topic that is useful for healthcare providers is a(n) systematic review.
In the field of science, a systematic review can be described as a summary of various medical research studies which are carefully studied, analyzed, and interpreted in order to answer a concerned question. A systematic review involves critical evaluation and high-end analysis of multiple studies which are done in detail that are useful to healthcare providers.
Data is extracted from various related research in a systematic review to reach to a decision point about a concerning topic. Systematic reviews help in discussion related to medical topics, to provide data for criticizing a certain topic, and to evaluate the gaps between various studies. A systematic review can also build up a topic for future research.
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Answer:
a. The sodium channels in his nerves will be blocked.
Explanation:
Tetracaine is an ester-type anesthetic and produces local anesthesia by blocking the sodium ion channels involved in initiation and conduction of neuronal impulses. Tetracaine is rapidly hydrolyzed in the plasma; therefore, volume of distribution could not be determined
Answer:
serotonin
Explanation:
Platelets release <u>serotonin</u>, a chemical vasoconstrictor that contributes to the vascular spasm.
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MD stands for Medicine doctor