Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Respiratory rate increased from 16 to 19 breaths per minute is vital signs during activity would be the best indicator that the client is tolerating mild exercise.
Your body utilizes more oxygen during exercise and creates more carbon dioxide when your muscles perform harder. Your breathing has to increase from about 15 times per minute while you are resting to about 40–60 times per minute while you are exercising in order to meet this additional requirement. To supply the body with oxygen more quickly, breathing rate rises. To more effectively get the oxygen (and glucose) to the breathing muscles, the heart rate increases. These procedures call for oxygen. Because of this, when an activity is completed, a person's respiration and pulse rate do not immediately return to normal. The oxygen debt is the quantity of oxygen needed to flush out the lactic acid and replenish the body's oxygen stores.
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A lot of these words are derived from the Greek or Latin roots that mean what the word is used to mean in English. It's helpful to look up the etymology or understand what these roots mean because they come up all the time and in different combinations. This way you can look at a word you've never seen before and know what it means by breaking it down into its component parts.
1. Surgical puncture to remove fluid = centesis
2. Inflammation = itis
3. Abnormal hardening = sclerosis
4. Surgical removal = ectomy
5. Vomit = emesis
6. Infection = sepsis
7. Involuntary contraction = spasm
8. Surgical opening = stomy
9. Specialist in = ologist
10. Process of recording = graphy
11. Instrument that records = graph
12. Oxygen = oxia
13. Seizure attack = ictal
14. Paralysis = plegia
15. Surgical repair = plasty
16. Disease = pathy
17. Study of = logy
18. Tumor = oma
19. Enlargement = megaly
20. Breathing = pnea
21. Malignant tumor = sarcoma
22. Narrowing = stenosis
23. Swallowing or eating = phagia
Rhinoplasty = surgical repair of the nose
Ateriosclerosis = abnormal hardening of the arteries
Neuropathy = disease of the nervous system
Postictal = after a seizure attack
Answer:
(B). inhibiting HMG-CoA reductase.
Explanation:
Lovastatin is a drug, which is used to reduce risk for cardiovascular diseases and to reduce level of cholesterol in blood.
It works by inhibiting HMG-CoA reductase (3-hydroxy-3-methylglutaryl-coenzyme A reductase) enzyme, required for the formation of mevalonate from HMG-CoA.
Mevalonate is building block for the biosynthesis of cholesterol. Hence, lovastatin inhibits cholesterol production by inhibiting synthesis of mevalonate.
Thus, the correct answer is option (B).
Answer:
Their need is fibrin. so you would take it away so you can analyze what would happen to the tissue if there is none.
Explanation:
