Prader-Willi syndrome (PWS) is a gentic disorder which has an impact on numerous physiological systems. PWS affected individuals (specifically babies) experience delayed growth, significant hypotonia (low muscle tone), and feeding issues. It does effect circadian rhythms in mice models.
SNORD116, often referred to as HBII-85, is a non-coding RNA (ncRNA) molecule that contributes to the alteration of other small nuclear RNAs (snRNAs). Unlike the majority of other snoRNAs, SNORD116 is not significantly complementary to ribosomal RNA and is expressed widely in the brain (but not in PWS patients).
According to the studies, SNORD116 cause sleep defect in patients with Prader-Willi syndrome. Same observation was seen in mouse models too. Paternal expression of SNORD116 is thought to be a potential gene for the sleep disruptions/circadian rhythm’s that the majority of PWS sufferers.
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Answer:
Donor coordination is meant to counteract this and has become an important item on the international development agenda.The underlying reason for this is the growing pressure to improve the efficiency and effectiveness of development cooperation exerted, on the one hand, by the ambitious Millennium Development Goals (MDGs) and the comprehensive poverty reduction strategies being pursued by many low-income countries and, on the other hand, by scarce development cooperation resources.
Explanation:
Answer:
The wechsler intelligence scale for children (WISC) is a good indicator of innate "genetic" ability for children of six to sixteen years old.
Explanation:
Wechsler Intelligence Scale for Children (WISC) is basically a system of testing IQ of children from six to sixteen years old. This testing was created by David Wechsler, who stated that intelligence is a global quality and it should be reflected in children's verbal as well as non-verbal abilities.
This testing system is used by schools for several purposes:
• To evaluate the performance of kids during placement process.
• It is also used to evaluate abilities of dis-abled children or deferentially able children.
• IQ scores from WISC can be used to diagnose the problems of the children such as mental re-tardation or some specific learning dis-ability. It can also be used to determine the problems of the children who face hyperactivity or attention deficiency.
• In addition, the test can also diagnose brain related and neuro-psychological disorder.
Point to remember:
The WISC system is not useful to determine the extreme form of intelligence like IQ below 40 and above 160. Wechsler himself focused on this point many times that test is not adequate for children with IQs of below 70 or above 130. Despite of this fact, people use this test to determine the intelligence of deferentially able children who usually have IQ above 130 that is not very appropriate thing.
<em>Note:</em><em> This answer is very generic based on the statement of the question. If you have some specific options of the questions, please post it again with them or comment. Thank you.</em>
Asexual reproduction produces <span>a direct clone of the parent.
The other terms are related to sexual reproduction.
Asexual reproduction or asexual reproduction is a mode of reproduction, which (as opposed to sexual reproduction) corresponds to the capacity of living organisms to multiply alone, without a partner, without involving the fusion of two gametes of opposite sexes.
The mechanism of the reproduction is by </span>mitosis, <span /><span>budding or </span>scissiparity.<span>
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Answer:
b. thick wall.
Explanation:
Endospore is a structure formed by some bacteria, that help them survive unfavourable conditions (e.g. lack of nutrients). This survival strategy of some bacteria (usually Gram+ bacteria) help them stay dormant for a while, until stressful conditions stop. A thick wall composed of many layers (exosporium, spore coat, spore cortex, core wall) of the endospore is what provides resistance to different stressful chemical and physical factors such as UV radiation, temperature, chemical damage etc.
