Question

What are the characteristics is associated with innate immunity?

Answer 1

Answer: First line of defense, the cells of the innate recognize and respond to pathogens in a generic and fast way and does not confer long-term or protective immunity. Recruitment of immune cells to the sites of infection and inflammation and activation of the complement system cascade.

Explanation:

Innate immunity is a defense system that you were born with and that protects you against all antigens. Innate immunity consists of barriers that prevent harmful materials from entering the body. These barriers form the first line of defense in the immune response. There are also phagocytic cells of the immune system which include: macrophages, neutrophils, and dendritic cells. The membrane receptors of those cells allow it to act on the recognition of danger signals and they are of the type TLR and PRR. These are Antigen Presenting cells which process the pathogens and display their antigens on their surface and takes it to B lymphocytes for the production of antibodies, which is part of the adaptive immune system.

This means that the cells of the innate recognize and respond to pathogens in a generic and fast way and, unlike the adaptive immune response, does not confer long-term or protective immunity to the host.

So, the main functions of the innate immune response include:

• Recruitment of immune cells to the sites of infection and inflammation, through the production of chemical factors, including specialized chemical mediators, called cytokines.

• Activation of the complement system cascade to identify bacteria, activate cells and promote clearance of dead cells or antibody complexes.

• The identification and removal of foreign substances present in organs, tissues, blood and lymph, by leukocytes.

• The activation of the adaptive immune response through a process known as antigen presentation.
• Inflammation is one of the first responses of the immune system to infection or irritation. It is stimulated by the release of chemical factors and serves to establish a physical barrier against the spread of infection, and to promote the recovery of some damaged tissue following clearance from pathogens. Chemical factors produced during inflammation (histamine, bradykinin, serotonin, leukotrienes) sensitize pain receptors, cause vasodilation of blood vessels at the scene, and attract phagocytes, especially neutrophils.