Pillow Talkin by Lil Dicky explains it all
Answer:
A frameshift changes every codon past it. A base substitution only changes one codon.
Explanation:
DNA is comprised of nucleotides (A, C, T, G) that make up amino acids. Every three bases is called a codon and represents an amino acid.
In a frameshift mutation, a nucleotide is either added or deleted from the sequence. This offsets the entire sequence after it because the reading frame shifts. Here's an example:
ACTGCTATCGTCATC
If another T is added in between the first and second codons, then every codon after will be changed.
ACT>T<GCTATCGTCATC
A substitution mutation is usually less severe, as it only alters one codon in the sequence. These occur when one nucleotide is replaced by another one. Here's an example:
ACTGCTATCGTCATC
Let's say the first G is replaced by a T.
ACT>T<CTATCGTCATC
As you can see, none of the other codons changed.
Typically, a frameshift mutation is considered worse than a substitution mutation.
Answer:
2 molecules of ATP
Explanation:
Glycolysis is the anaerobic process (no oxygen required) used in the breakdown of glucose to extract energy. It occurs in the cytoplasm of both prokaryotic and eukaryotic cells. It is the first step of cellular respiration.
Glycolysis is subdivided into two phases: the first phase uses energy (ATP), while the second phase produces it together with pyruvate and NADH.
Two molecules of ATP are required for the first stage of glycolysis, while 4 ATP molecules and 2 NADH molecules are formed in the second stage.
