The answer to this is C. Industry. It's the only man made factor.
D is the answer because carbondioxide and oxygen are both needed for plants or green plants to survive.
I hope it helped
Biotechnology can be used to transform bacteria so they are able to make human proteins, such as insulin. It can also be used to create transgenic crops, such as crops that yield more food or resist insect pests. (I copied this off the web so just paraphrase)
A Butterfly has Four Stages