Question

An important characteristic of antibacterial drugs is their selective toxicity. if antibacterial drugs were not selectively toxic, then they would kill or interfere with the hosts' cells as well as bacterial cells. examining cellular differences between bacterial (prokaryotic) cells and host (eukaryotic) cells suggests strategies to achieve selective toxicity. we can capitalize on these differences and take advantage of them in the design of antibacterial drugs identify antibacterial strategies that would likely be selectively toxic for bacteria.

Answer 1

Answer;

-inhibition of peptidoglycan synthesis

-inhibition of fimbriae synthesis

-interfering with translation at 70s ribosomes

Explanation;

- Selective toxicity refers to the ability of the drug to targets sites that are relative specific to the microorganism responsible for infection. Sometimes these sites are unique to the microorganism or simply more essential to survival of the microorganism than to the host.

-Antibacterial action generally falls within one of four mechanisms, three of which involve the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, or protein synthesis, respectively. The fourth mechanism involves the disruption of membrane structure.