An important characteristic of antibacterial drugs is their selective toxicity. if antibacterial drugs were not selectively toxi
c, then they would kill or interfere with the hosts' cells as well as bacterial cells. examining cellular differences between bacterial (prokaryotic) cells and host (eukaryotic) cells suggests strategies to achieve selective toxicity. we can capitalize on these differences and take advantage of them in the design of antibacterial drugs identify antibacterial strategies that would likely be selectively toxic for bacteria.
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Selective toxicity refers to the ability of the drug to targets sites that are relative specific to the microorganism responsible for infection. Sometimes these sites are unique to the microorganism or simply more essential to survival of the microorganism than to the host.
-Antibacterial action generally falls within one of four mechanisms, three of which involve the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, or protein synthesis, respectively. The fourth mechanism involves the disruption of membrane structure.
Endangered species are generally those whose population is declining or in a very limited range. Some of other characteristics of endangered species may also be habitat loss, indiscriminate hunting by man or predators, and disease.
the end or close; final part. the last main division of a discourse, usually containing a summing up of the points and a statement of opinion or decisions reached. ... final decision: The judge has reached his conclusion. a reasoned deduction or inference.
