Answer:
The correct option is : <u>C. prevent the immune system from responding to self-antigens</u> and <u>D. prevent excessive response to foreign antigens </u>
Explanation:
<u>Immune tolerance</u>, also known as the immunotolerance, of the immune system, is a state of unresponsiveness to the cells or tissues that are capable of eliciting an immune response in an organism.
Tolerance is classified into <u>central and peripheral. </u>The central tolerance is induced in the thymus and bone marrow. Whereas, the peripheral tolerance is induced in the other tissues and the lymph nodes.
<u>Central tolerance of the immune system is responsible for discriminating the self cells from the non-self cells of the body and thus prevents the body from responding to self-antigens.</u>
<u>Peripheral tolerance of the immune system is responsible for preventing excessive response of the immune system to foreign antigens like allergens.</u>
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