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Answer:
interspersed, transposon-derived repeats, simple sequence repeats.
Explanation:
In the human genome, not only the protein coding genes are present, in fact these genes make up just a very little portion of the human genome about 1.5-2% of the entire human genome. Repeats make up about 48% of the human genome which is the largest and the rest include, conserved non coding sequences (43.5%), heterochromatin regions etc.
Some of the repetitive elements includes LINEs, SINEs, DNA fossils tranposoon, Retrovirus like elements. all these are transposable elements which are mobile DNA sequences that can migrate to different regions/areas of the genome.
Microsatellites (simple sequence repeats) are tracts of repetitive DNA in which certain DNA motifs are repeated normally 5-50 times.
If your body has developed a tolerance to a medication you're taking, it means the medication at your current dose has stopped working as effectively as it once did. It might mean your body becomes used to the medication, and you don't get the same benefits or effects as before. Drug tolerance is indicative of drug use but is not necessarily associated with drug dependence or addiction. The process of tolerance development is reversible and can involve both physiological factors and psychological factors.
Answer:
The correct answers are option A. "tethering proteins to the cell cortex", B. "using barriers such as tight junctions", C. "tethering proteins to the extracellular matrix", D. "forming a covalent linkage with membrane lipids", E. "tethering proteins to the surface of another cell"
Explanation:
According to the fluid-mosaic model, the components of cell membranes are in constant movement forming a barrier to avoid unwanted exterior component internalization and to avoid the loss of precious internal components. This constant movement could cause that proteins move across the plasma membrane. But, this is avoided by several mechanisms including:
A. Tethering proteins to the cell cortex. The cell cortex is a rigid structure made of actin and actomyosin. Proteins found in the plasma membrane are tethered to this structure to restrict their movement.
B. Using barriers such as tight junctions. Tight junctions are barriers found in epithelia made of claudin and occludin proteins. These barriers are impenetrable, which avoid the movement of proteins in the cell membrane.
C. Tethering proteins to the extracellular matrix. The extracellular matrix is made of several proteins and macromolecules that provide a structural and biochemical support to cells that are nearby. Proteins could be tethered to this rigid structure as well.
D. Forming a covalent linkage with membrane lipids. The proteins in the cell membrane that form a covalent linkage with membrane lipids are known as lipid-anchored proteins, or lipid-linked proteins.
E. Tethering proteins to the surface of another cell. When cell-cell communication take place it is possible that proteins in the cell membrane got tethered to the surface of the other cell.