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pychu [463]
2 years ago
11

Nails are an extension of what layer of the epidermis?

Biology
2 answers:
Fynjy0 [20]2 years ago
8 0

Answer:

<h2><em><u>The Squamous Cell Layer</u></em></h2>

Explanation:

mark as brainliest and drop some thanks!!!

arsen [322]2 years ago
3 0

Explanation:

The nail bed, is a specialised form of skin epithelium, and has the same four layers of the epidermis of skin, with the nail plate being analogous to the stratum corneum layer. The nail plate is made up of tightly packed, hard, keratinized epidermal cells.

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In colorectal cancer, some tumor suppressor genes are inactive. This is an important factor resulting in uncontrolled cell divis
tresset_1 [31]

Answer/Explanation:

(1) a mutation in the coding region, resulting in an inactive protein

To check to see if there is a mutation, you could extract the DNA from the cancer cells and then perform PCR to amplify the gene of interest. You could then perform sanger sequencing and compare the sequence to the normal gene to see if a mutation is present. To test the effect of the mutation, you would want to see if an active protein has been formed.

To see if a normal sized protein has been formed, you could perform a western blot, comparing the protein band to the WT protein band. If the protein is absent or much smaller, it is likely not a functional protein.

(2) epigenetic silencing at the promoter of the gene, resulting in reduced transcription.

To check for changes in the epigenetic landscape of the promoter, you could perform chromatin immunoprecipitation by extracting the chromatin from the tumour cells and using antibodies for different chromatin marks to see what has changed between the normal cells and the tumor cells. E.g. H3K9me3, H3K27me3. You would perform a pull down with the antibody of interest and then PCR for your promoter to specifically look at changes at that gene compared to normal cells. To test DNA methylation, you could perform bisulfite sequencing.

To see how transcription is affected, you could extract RNA from the tumor and normal cells, and compare the levels of RNA between the two samples by qRT-PCR

3 0
2 years ago
PLEASE HELP!!!
LUCKY_DIMON [66]
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<h2>__________________</h2><h2>FOLLOW ME</h2>
7 0
2 years ago
The nature of scientific investigation
evablogger [386]

Answer: make systematic observations and carefully collect relevant evidence.Then they use logical reasoning and some imagination to develop hypotheses and explanations.

//Give thanks if helpful :)//

Explanation:

6 0
3 years ago
Skeletal muscles are involved in:
user100 [1]

Answer: I would say D.

Explanation:

 Sorry if wrong.

4 0
2 years ago
What is the first thing that can cause a change in allele frequency?
kogti [31]

Answer: <u><em> Microevolution is defined as a change in allele frequencies in a population over time. Three mechanisms can cause allele frequencies to change: natural selection, genetic drift (chance events that alter allele frequencies), and gene flow (the transfer of alleles between populations).</em></u>

Explanation:<u><em> If i'm right Mark Me brain, give 5 stars and a thank you</em></u>

<u />

8 0
2 years ago
Read 2 more answers
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