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GuDViN [60]
3 years ago
10

A. You are performing experiments with your protein of interest and its ligand. You are attempting to mutate the binding site of

your protein to disrupt binding to ligand to see what happens inside the cell. You make a series of mutations and one in particular gives you surprising results: you observe that the mutation that you made in an amino acid that sticks out into the binding pocket actually increases the protein’s affinity for the ligand. Give a molecular explanation for these results
Biology
1 answer:
kirza4 [7]3 years ago
3 0

Answer:

The ability of a protein to bind to its receptor depends on formation of noncovalent interactions with it. These interactions include hydrogen bonds, ionic bonds, van der Waals attractions and hydroph.

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4 0
3 years ago
LD
Arturiano [62]

Answer:

The best explanation for the increased lymphocyte levels in Kaya is that she was not tissue typed prior to her surgery, and her body is mounting an immune response.

Explanation:

When performing an organ transplant, it must be verified whether the organ to be transplanted is compatible -by tissue typing- with the recipient, since it is recognized as a foreign body by the body and can be rejected.

One of the immunological responses to organ rejection is called cell rejection, involving T-helper and cytotoxic lymphocytes.

<u>It is very likely that in Kaya's case the tests have not been performed correctly, and she is experiencing rejection of the organ she received</u>. The progressive increase in lymphocytes may be an indication of this.

The other options are not possible because:

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