Pro-won’t spread
Con-there could still be some left of it. Not all viruses can be destroyed completely. Does that make sense?
Answer/Explanation:
DNA polymerase is the enzyme responsible for replicating DNA. It is hugely important that is performs its functions accurately, as if incorrect bases are incorporated this can lead to mutations that disrupt the structure and function of genes. It adds nucleotides in a 5' - 3' direction only.
DNA polymerase III also has high processivity, which means that for every time it binds DNA, it is able to add many bases before it becomes dissociated.
A. DNA polymerase avoids the incorporation of improperly paired nucleotides in two ways:
- The first way depends on the structure of the enzyme. If the nucleotide that the enzyme is in the process of adding is not complementary to the template, then the nucleotide will not align with the template, and thus it is more inefficient to add. This inefficiency means the nucleotide is more likely to leave the active site before it is added, and DNA polymerase can replace it with the correct nucleotide.
- It also has proofreading capabilities. This means, when an incorrect base is added, it recognises the error and can fix this. It can do this because it possesses 3'-5' exonuclease activity. That means, it can chop out incorrectly added bases.
B. Ribonucleotides are the nucleotides that are incorporated into a growing RNA molecule. They are different from deoxyribonucleotides because of the differences in the sugar backbone (ribose vs deoxyribose). Their incorporation would disrupt the structure and function of the DNA, leading to problems with transcription and replication.
DNA polymerase avoids incorporating these nucleotides primarily because of the structure of the enzyme. Ribonucleotides cannot fit into the active site of DNA polymerase due to what is called a "steric filter" or "steric gate". This gate/filter function is performed by specific amino acid residues which usually have a bulky side chain and thus block the incorporation of the 2'OH of the ribose sugar (which is lacking in the deoxyribose sugar)
Should I Become a Genetic Counselor?
Genetic counselors help educate people about their chances of inheriting genetic disorders or diseases using information from a patient's family medical history. They explain possible testing options and provide support to patients and family members. They also might educate other healthcare professionals, students, and the public about genetic disorders. Sharing potentially upsetting results with clients can be stressful.
Career Requirements
Degree Level Master's degree
Degree Field Genetic counseling, biology, psychology, or related field
Licensure and Certification Certification is required by some employers; licensing is required by many states
Experience Experience requirements vary by employer, but generally the minimum is two years
Key Skills Excellent writing, communication, and decision-making skills; knowledge of human mutation databases and genome browsers; knowledge of Human Genome Variation Society (HGVS) nomenclature
Median Salary (2015) $72,090
Source: U.S. Bureau of Labor Statistics
Steps to Become a Genetic Counselor
Step 1: Earn a Bachelor's Degree
A bachelor's degree in biology or a healthcare-related field typically is a requirement for enrolling in a genetic counseling master's degree program. These programs provide students with the science and math knowledge needed for a career in genetic counseling. Coursework focused in genetics, biochemistry, and statistics is valuable to future genetic counselors.
Some schools offer internships or summer programs for students interested in genetic counseling. These programs provide students with a chance to gain experience at clinics or hospitals and prepare them for a graduate degree program. Also consider doing volunteer work or providing counseling. Performing work for a crisis hotline or reproductive counseling service can help provide the skills and qualifications needed for a graduate program in genetic counseling.
Step 2: Earn a Master's Degree
A master's degree in genetic counseling usually is required for genetic counselor positions. These programs typically provide coursework in human genetics, lab work, counseling, and research. Students develop the skills needed to research, counsel, and consult with patients, their families, and members of the healthcare community to provide information on genetic conditions. Admission requirements usually include a bachelor's degree with credits in genetics, biochemistry, and statistics. Some schools require applicants to have performed some type of counseling work.
Step 3: Get Certified/Licensed
The American Board of Genetic Counselors (ABGC) offers a certification program. This certification is technically voluntary; however, some states require it for licensing, and some employers prefer it. In addition, some states require genetic counselors to become licensed before performing work with the public. Certification requirements include completion of a graduate degree program in genetic counseling through an ABGC-accredited program and passage of a written exam. ABGC certification can serve as proof of competency and give job candidates an edge in employment.
Step 4: Gain Work Experience
Entry-level positions allow genetic counselors to work under supervision, assessing patients, and providing counseling. More advanced positions allow genetic counselors to work independently at these duties, in addition to performing research and providing education to the public and healthcare professionals. The National Society of Genetic Counselors (NSGC) provides individuals with online education resources and opportunities to network with other members of the field. Courses go over self-marketing, mentoring, and instructional guides on starting a clinic.
Genetic Counselors need a field-specific master's degree, and certification and state licensure might be required.
Answer:
Primary consumers
They eat the majority of prey
