1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Lostsunrise [7]
3 years ago
11

Protein disulfide isomerase (PDI) is a protein folding enzyme that catalyzes disulfide–sulfhydryl exchange reactions. Ribonuclea

se is an enzyme with two β-sheets, three α-helices, and four disulfide bridges critical to the stability of its structure. PDI rapidly converts inactive, scrambled ribonuclease to enzymatically active ribonuclease. This process is driven by the decrease in free energy as the scrambled conformations are converted into the stable, active conformation of the enzyme. In contrast, PDI rapidly inactivates insulin. What does PDI's effect on insulin imply about the structure of insulin? The three‑dimensional shape of insulin does not contain any disulfide bonds. The active conformation of insulin has more β-sheets than α-helices. The amino acid sequence of insulin is similar to the amino acid sequence of ribonuclease. The active conformation of insulin is not the most thermodynamically preferred form.
Biology
1 answer:
lakkis [162]3 years ago
3 0

Answer:

The effect of protein disulfide isomerase on insulin signifies that the active conformation of insulin is not the most thermodynamically favored form. The main reason behind this is that the protein disulfide isomerase seems to decline the free energy, that is, it makes them more steady form predominant.  

In the case of insulin, the prevalence of the stable form results in its inactivation. Thus, it signifies that the active form is not thermodynamically stable.  

You might be interested in
The processes of photosynthesis and carbon fixation are identical in all plants.
slavikrds [6]

Answer:

F

Explanation:

Some plants follow C3 pathway while some follow C4 pathway

7 0
3 years ago
Read 2 more answers
Question 1
Nadusha1986 [10]

Answer:

adenine is the correct answer for first

4 0
3 years ago
Proteins do not pass through cell membranes because.
NeX [460]

Answer:

Proteins are generally way too big to be able to fit through a cell membrane.

Explanation:

They cannot compress their molecules to pass through.

4 0
2 years ago
56:51<br> Collecting research data is the final step in the scientific method.<br> True or false
Svetradugi [14.3K]
The answer for this question is False
4 0
3 years ago
Read 2 more answers
What are the three primary elements of a healthful eating plan?
alexgriva [62]
They should be carbohydrates, fats (lipids) and protein. they are labelled as primary food substances and they're essential to life. they can provide energy and raw material for life processing. although mineral ions and vitamin are important too, but they only need a small amount.
5 0
3 years ago
Other questions:
  • Skin cancer is to exposure to uv radiation as
    14·1 answer
  • IN THE FOOD CHAIN,CONCENTRATIONS OF HARMFUL SUBSTANCES MAY INCREASE IN HIGHER LEVELS IN THE FOOD CHAIN IN PROCESS KNOWN AS
    9·1 answer
  • Wich event will follow dna replication in a cell cycle
    11·1 answer
  • Why did Gregor Mendel choose to use pea plants
    8·2 answers
  • Why is there diversity of life on Earth?
    6·1 answer
  • What traits are taken into consideration during classification in plants
    5·2 answers
  • Which part of the wave has the highest frequency
    11·2 answers
  • Answer could be <br> A.)3/16<br> B.)9/16<br> C.)11/16<br> Or D.)13/16
    11·1 answer
  • What is the journey of oxygen through our lungs?
    14·1 answer
  • Word Bank :
    9·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!