Answer:
Pioneers faced diseases with no help from doctors nearby.
Explanation:
James Madison was the president
Answer: Missouri's admission as a slave state
Explanation: The Missouri Compromise was a US federal statute that allowed Missouri to be a slave state and Maine to become a free state in exchange for anti-slavery legislation.
After the disaster in Lisbon, Shay was furious with the plans of the Colonial branch of the Assassin Brotherhood. So he became a templar and devoted his career to hunting down artifacts and his former associates.His travels brought him to New York, the Appalachian mountains, among other locations.