1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
serious [3.7K]
3 years ago
10

Let's suppose you were interested in developing drugs to prevent epigenetic changes that may contribute to cancer. What cellular

proteins would be the target of your drugs?
Biology
1 answer:
Vaselesa [24]3 years ago
5 0

Answer:

Potential targets:

1- DNA methyltransferases

2- Chromatin modifiers such as histone acetyltransferases, histone deacetylases, histone methyltransferases, etc.

3- Components of the RNA interference (RNAi) machinery such as Dicer, Argonaute, etc.

Explanation:

Epigenetics can be defined as the study of any heritable change in the phenotype that does not involve modifications in the DNA sequence. Epigenetic mechanisms can be classified into three major types: 1-DNA methylation, 2-histone modifications (e.g., acetylation, methylation, phosphorylation, etc), and 3-regulatory non-coding RNAs (e.g., miRNAs, lncRNAs, siRNAs, etc) that modulate target gene expression via the RNA interference pathway. There are different types of proteins that are involved in these complex epigenetic mechanisms, and those cited above represent only some examples that can be used as therapeutic targets.

You might be interested in
Other than bacteria, which factor leads to nitrogen fixation? A. Lightning B. Flood C. Rain
max2010maxim [7]

Answer:

A. Lightning

Explanation:

Nitrogen is very fundamental for a wide range of life activities in both plant and animals.

Lightning which accompanies thunder during rain storm and other weather phenomenon aids the release of atmospheric nitrogen for life processes. The energy that accompanies a lightning event is mostly electrical in nature. This electrical energy is huge and very massive. As the lightning interacts with free nitrogen molecules in the atmosphere, the molecule is broken down. The free nitrogen which results then combines with oxygen in the atmossphere to form oxides of nitrogen. When oxides of non-metals dissolves in rain water, they make the water rich in nitric acid and can be brought to the biosphere for use by plant and animals.

6 0
4 years ago
What is photosystem 1 and photosystem 2 and what do they do? What are the steps ?
lesantik [10]

P I and PII are proteic compounds present in the thylakoid membrane that contain about 300 chlorophyll molecules each.

<h2><em><u>Step I</u></em></h2>

First of all light with a wavelength of 690nm is absorbed by P II. The light excites an  electron that leads to the photolysis of water(H2O--->2H+ +2e- + 1/2O2). The two electrons released go into the electron transport chain. The second compound in electron transport chain is plastoquinone that is reduced when it accepts electrons then oxidised when it loses them to P I. The next two compounds are cytocromes  that make  hydrogen protons  go inside the thylakoid when they recieve the electrons.(I will mention what happens to the  H+  in the second step). The next compound in the electron transport chain is a compound that contains Fe and S. The electrons finally reach the last step: Reduction of NADP+ to NADPH+H+.

<h2><em><u>Step II</u></em></h2>

In the second step is ATP synthesis. Hydrogen protons accumulate inside  the thylakoid membrane. An electrochemical gradient is formed. The protons can leave the thylakoid according to this gradient through an enzyme.

When the protons flow through , it turns ADP into ATP.

<u>To sumarize: the role of P II is O2 production through photolysis and ATP synthesis(indirectly) The role of P I is NADPH+H+ synthesis.</u>

<em><u /></em>

3 0
3 years ago
What valve prevents back flow into the left ventricle of the heart?
Rom4ik [11]

Answer:

Option D, aortic valve

Explanation:

The location of aortic valve i.e between the aorta and left ventricle,  allows it to stop the blood from flowing back into the left ventricle.

The other options are incorrect as -  

Pulmonary valve being located between the pulmonary artery and right ventricle, stop the blood from flowing back into the right ventricle.

The tricuspid valve and mitral valve stops the blood from flowing back into the right atria and left atria respectively.  

Hence, option D is correct.

4 0
3 years ago
What is the nutrient used to petri dishes to grow bacteria?​
rosijanka [135]
Sterile powdered agar with nutrients can be mixed with water, heated and then poured into empty petri plates or ready-to-use dishes can be purchased. The undigestible agar is a gelatin-like substance with a semi solid surface on which the bacteria can grow while they consume the added nutrients (like sheep's blood).
8 0
3 years ago
 HOW WOULD YOU BE ABLE<br> TO IDENTIFY streptococci THROUGH A MICROSCOPE
Margarita [4]
Actually i just happen to be smart at this one and the answer above is wrong look it up. cocci bactertia are a spherical shape and this one particularly will be single notice cocci not coccous. no offense to answer above
4 0
3 years ago
Other questions:
  • The diagram above shows a food web. What is a food web?
    14·2 answers
  • What distinguishes science from art, architecture, and philosophy?
    12·1 answer
  • Which of the following is the best defenies species​
    11·1 answer
  • From a physiological standpoint, the best breathing technique requires the lifter to inhale when lowering the weight and exhale
    11·1 answer
  • Free points~<br><br> Things will get better soon, I promise. Keep going, you’ll see.
    15·2 answers
  • Kendra wishes to build a model of a carbohydrate molecule, ideally containing as many monomers as possible. Which set should she
    15·1 answer
  • John hears a musical song while in an fMRI. The researcher tells John that his left hemisphere was more activated True or false?
    8·1 answer
  • Describe how alleles and genes are created
    7·1 answer
  • How is Anaphase I in meiosis different than in mitosis
    8·2 answers
  • Please help
    8·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!