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serious [3.7K]
2 years ago
10

Let's suppose you were interested in developing drugs to prevent epigenetic changes that may contribute to cancer. What cellular

proteins would be the target of your drugs?
Biology
1 answer:
Vaselesa [24]2 years ago
5 0

Answer:

Potential targets:

1- DNA methyltransferases

2- Chromatin modifiers such as histone acetyltransferases, histone deacetylases, histone methyltransferases, etc.

3- Components of the RNA interference (RNAi) machinery such as Dicer, Argonaute, etc.

Explanation:

Epigenetics can be defined as the study of any heritable change in the phenotype that does not involve modifications in the DNA sequence. Epigenetic mechanisms can be classified into three major types: 1-DNA methylation, 2-histone modifications (e.g., acetylation, methylation, phosphorylation, etc), and 3-regulatory non-coding RNAs (e.g., miRNAs, lncRNAs, siRNAs, etc) that modulate target gene expression via the RNA interference pathway. There are different types of proteins that are involved in these complex epigenetic mechanisms, and those cited above represent only some examples that can be used as therapeutic targets.

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oksano4ka [1.4K]
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Socratic can help! This learning app, powered by Google AI, helps you understand your school work at a high school and university level. Ask Socratic a question and the app will find the best online resources for you to learn the concepts.

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3 years ago
Which of the following is not a main characteristic of a mineral?
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D. Man-Made is the answer
4 0
2 years ago
Arrange the three kinds of nitrogenous wastes based on the energy required to synthesize them, beginning with the waste product
Evgen [1.6K]

the three kinds of nitrogenous wastes based on the energy required to synthesize them are arranged; Ammonia < urea < uric acid.

Nitrogenous wastes are the nitrogen compounds that organisms use to get rid of excess nitrogen. Ammonia, urea, and uric acid are the most common nitrogenous wastes that animals excrete. Protein metabolism generates all of these nitrogenous wastes.

Ammonia is the most toxic of these nitrogenous wastes, and it is the most common but requires the least energy. Urea is more harmful than uric acid, but it is less harmful than ammonia, reducing the amount of energy required to synthesize it. Uric acid is the least harmful, a non-poisonous particle with four nitrogen molecules. This is useful for birds and reptiles that lay hard eggs because it eliminates the most nitrogen, uses the least amount of water, and is not toxic. It also takes the most energy input.

Know more about urea here: brainly.com/question/14453829

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3 0
1 year ago
A mutation results in the production of much less dna ligase than normal. what would be a likely consequence?
ss7ja [257]
DNA ligase is the enzyme that repair irregularities and breaks in the back bone of double stranded DNA. The enzyme function by sealing the repair in the DNA, it seals recombination fragments and it connects okazaki fragments during replication of DNA. 
If a mutation reduce the amount of ligase, all the functions of the ligase enzyme listed above will be affected negatively.
4 0
3 years ago
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Why is it impossible for offspring to show recessive trait if one parent is homozygous for the dominant trait?
Luden [163]

If you make a punnet square out of this, there is no possibility to have a recessive trait because neither parents have it plus dominant is always going to overrule recessive traits.

5 0
2 years ago
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