The antimicrobial activities in the mouth are hydrochloric acid denatures proteins and killing many microbes.
The capability of an hydrochloric acid activating pathogen-killing compounds is not a part of insect immunity,There has recently been an increase in interest in trehalose metabolism for therapeutic applications due to trehalose's relevance in numerous pathogenic species.The most significant biosynthetic process is the enzyme TPP (trehalose-6-phosphate phosphatase) (OtsAB).
Here, five important nematode and bacterial pathogens' recombinant TPPs, including three new members of this protein family, are compared for their enzyme characteristics.
The kinetics of the hydrolysis of trehalose-6-phosphate show that all five enzymes display burst-like kinetic behaviour, which is characterised by a decrease in enzymatic rate beyond the pre-steady state.
The observed super-stoichiometric burst amplitudes can be explained by many global conformational changes that occur in members of this enzyme family during substrate processing.
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The gene transfer process in bacteria is also commonly known as the "horizontal gene transfer." In this process, the DNA of a bacteria is transferred from one bacterium to another virus, through a plasmid from a donor cell to a recipient cell.
