Proteins that are functionally less important for the survival of an organism generally evolve faster than more important proteins.
Proteins serve as the building blocks for all of life's essential processes. The proteins evolve along with the genes that create them, adding new functionality or features that may potentially result in the development of new species.
The mutation of amino acid-coding nucleotides and the stabilization of novel variations in the population are the two phases required for protein evolution.
The stability of a protein's folded structure, how well it prevents aggregation, and how well it is chaperoned all affect how quickly it evolves. According to the studies, the degree of a protein's expression has a greater influence on its evolutionary rate than does the protein's functional significance.
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An intron is a non-coding region of DNA. During alternative splicing, introns are removed.
- During eukaryotic transcription, a fragment of DNA (e.g., a gene) is used as a template to synthesize a complementary RNA sequence, usually a precursor mRNA (pre-mRNA).
- Subsequently, this pre-mRNA is processed by a mechanism called alternative splicing in order to produce a mature mRNA which is then used as template to synthesize a protein by a process called translation.
- During alternative splicing, non-coding regions of a gene called 'introns' are removed, where coding regions called 'exons' are spliced back together.
- If a cell transcribed and translated a gene’s intron by mistake, then additional amino acids would be inserted into the protein and therefore the resulting protein will be longer than normal.
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