Enzymes belong to the proteins category because enzymes are long chains of amino acids bound together by peptide bonds
Enzymes have a special marker on them called an active site that, like a puzzle piece, fits with only one other type of molecule, generally referred to as a substrate. The substrate is a molecule that will undergo a reaction that results in it splitting into two separate molecules, called products
The substrate-specific to a particular enzyme will bind at the active site, forming what is known as an enzyme/substrate complex. In other words, a complex formed by the union of the enzyme and substrate
Hence, the right answer is option E "both A and B"