Adrenaline
Nicotine is a substance that is addictive in nature commonly
found in cigarette, that affect the nervous system by binding to the receptors
in the brain and other part of the body. Atherosclerosis is the loss of
elasticity or thickens of arteries walls. However, nicotine increases the
release of neurotransmitter adrenaline into the blood which subsequently cause
the development of atherosclerosis.
Your answer would be Sand.
If you go to the beach, and try making balls in your hand it's nearly impossible. If you pick up sand it will just fall through the crevice's in your hand, or a simple movement of your hand can make the sand fall. Sand simply can't be formed into a ball.
If you where to try making a ball of sand the outcome wouldn't be great. Even if you made the sand damp you still can't really make a ball of sand.
In 1884, a bacteriologist named Christian Gram created a test that could determine if a bacterium had a thick, mesh-like membrane called peptidoglycan. Bacteria with thick peptidoglycan are called gram positive. If the peptidoglycan layer is thin, it's classified as gram negative.
