Protective equipment is important because it exist as a preventative measure for industries that are known to be hazardous.
To summarize, food intake is influenced by metabolic activity in hypothalamic neurons and elsewhere; by hormones that signal the body's fat content to the brain; and by other homeostatic-need situations such as low blood glucose. All of these represent instances of negative feedback.
Yes it does the chemicals in whatever you are smoking are more than likely altered from what it originally was, therefore the chemicals start to taint the blood vessels and damage them permanently.