A manic depressive illness also known as bipolar disorder, is a serious mental disorder in which the person experiences extreme mood swings ranging from manic highs to depressive lows. The manic highs includes high energy, abnormally elevated mood and reduced need for sleep. Whereas, depressive lows include low energy, loss of interest and even suicidal thoughts.
Therefore, bipolar disorder causes manic-depressive illness in an individual.
The hormone cortisol is released in response to stress. Studies suggest that the high levels of cortisol from long-term stress can increase blood cholesterol, triglycerides, blood sugar, and blood pressure. These are common risk factors for heart disease