It would be "germs and disease" that had the greatest impact when the Old and New Worlds met, since the Natives in the New World were not immune to the germs that the Europeans were carrying--leading thousands of Natives to be killed.
Thomas Paine says that the colonies need to stop being afraid of the British and fight back for independence
The secret police attempted to identify citizens who opposed the Communist Party and who could undermine it.
FBI and CIA agents broke into the offices of the Democratic Party and George McGovern months before the election.
So, the answer would be to obtain information about Nixon’s opponents.